Stereotactic radiotherapy for spine and non-spine bone metastases: A pattern-of-care analysis in German speaking countries
Study PI:
Dr. med. Franziska Nägler
Franziska.naegler@medizin.uni-leipzig.de
Prof. Dr. Dr. Nils Nicolay
nils.nicolay@medizin.uni-leipzig.de
Study design:
- online survey among radiation oncologists (ROs) registered with the interdisciplinary working group Radiosurgery and Stereotactic Radiotherapy of the German Society of Radiation Oncology (DEGRO) and German Society for Medical Physics (DGMP)
Study objectiev:
- Bone metastases constitute a common indication for both conventional radiotherapy (RT) and stereotactic body radiotherapy (SBRT). Although in recent years guidelines have been proposed for SBRT of spine and non-spine metastases, little is known about the usage of bone SBRT and the actual patterns-of-care in German-speaking countries
Project status:
- Data collection completed
- manuscript currently under review
Major findings and results:
- 35 % (75/211) of registered ROs completed the online survey.
- ROs working in high-volume centers irradiating more than 100 patients with bone metastases annually represented the largest group with 58.7 %.
- Ablative SBRT was mostly performed for bone oligometastases (78.7 %).
- For symptom-directed palliative radiotherapy of bone metastases, the majority of responding physicians (84.3 %) still mostly recommended moderately hypofractionated treatment. Nevertheless, 60.9 % of participating ROs stated to use bone SBRT at least occasionally also for palliative purposes such as pain control.
- Survey also revealed a certain reluctance for the concomitant use of systemic therapies with bone SBRT and a heterogeneity regarding target volume definition and dosing for bone SBRT.
Stereotactic radiotherapy for bone metastases: a multicentre analysis
Study PI:
Dr. med. Franziska Nägler
Franziska.naegler@medizin.uni-leipzig.de
Prof. Dr. Dr. Nils Nicolay
nils.nicolay@medizin.uni-leipzig.de
Collaboration partners:
- Dr. med. Lena Kästner/ PD Dr. med. Dr. rer. nat. Judit Boda-Heggemann, University Hospital MannheimDr. med. Olaf Wittenstein/ PD Dr. Oliver Blanck, University Hospital Schleswig-Holstein
Study design:
- multicenter retrospective study
- The retrospective analysis will help to design a prospective registry for bone SBRT that will be open for participation for all WG members
Study objective:
- To evaluate efficacy and safety of SBRT for bone metastases in a defined patient population (several subgroups) and multicenter setting
- To identify patients who will benefit most from this approach and to establish binding SBRT-dose concepts and better define the combination with systemic treatments
Project status:
- Data collection for retrospective analysis