{"id":3617,"date":"2025-04-10T12:11:45","date_gmt":"2025-04-10T10:11:45","guid":{"rendered":"https:\/\/www.degro.org\/radiobiologie\/?page_id=3617"},"modified":"2026-09-30T11:54:02","modified_gmt":"2026-09-30T09:54:02","slug":"fokusgruppe-intrinsische-strahlensensibilitaet","status":"publish","type":"page","link":"https:\/\/www.degro.org\/radiobiologie\/fokusgruppe-intrinsische-strahlensensibilitaet\/","title":{"rendered":"Fokusgruppe: Intrinsische Strahlensensitivit\u00e4t"},"content":{"rendered":"<div id=\"pl-3617\"><style scoped>#pgc-3617-0-0 , #pgc-3617-0-2 { width:20.038% } #pgc-3617-0-1 { width:59.925% } #pg-3617-0 .panel-grid-cell { float:left } #pl-3617 .panel-grid-cell .so-panel { margin-bottom:30px } #pl-3617 .panel-grid-cell .so-panel:last-child { margin-bottom:0px } #pg-3617-0 { margin-left:-15px;margin-right:-15px } #pg-3617-0 .panel-grid-cell { padding-left:15px;padding-right:15px } @media (max-width:780px){ #pg-3617-0 .panel-grid-cell { float:none;width:auto } #pgc-3617-0-0 , #pgc-3617-0-1 { margin-bottom:30px } #pl-3617 .panel-grid , #pl-3617 .panel-grid-cell {  } #pl-3617 .panel-grid .panel-grid-cell-empty { display:none } #pl-3617 .panel-grid .panel-grid-cell-mobile-last { margin-bottom:0px }  } <\/style><div class=\"panel-grid\" id=\"pg-3617-0\" ><div class=\"panel-grid-cell\" id=\"pgc-3617-0-0\" ><div class=\"so-panel widget widget_sow-editor panel-first-child panel-last-child\" id=\"panel-3617-0-0-0\" data-index=\"0\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<p><strong>Fokusgruppensprecher:innen<\/strong><\/p>\n<p><img loading=\"lazy\" class=\"alignleft wp-image-3659 size-full\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/Ulrike_Theiss.png\" alt=\"\" width=\"160\" height=\"160\" srcset=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/Ulrike_Theiss.png 160w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/Ulrike_Theiss-150x150.png 150w\" sizes=\"(max-width: 160px) 100vw, 160px\" \/><br \/>\n<a href=\"https:\/\/www.ukgm.de\/ugm_2\/deu\/umr_rth\/umr_rth_team.php?id=9611\">Ulrike Thei\u00df<\/a><br \/>\nLeiterin Labor Strahlentherapie AG Molekulare Strahlenbiologie<br \/>\nUniversit\u00e4tsklinikum Marburg<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-3831 size-medium\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-200x300.jpg\" alt=\"\" width=\"200\" height=\"300\" srcset=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-200x300.jpg 200w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-683x1024.jpg 683w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-768x1152.jpg 768w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-1024x1536.jpg 1024w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-1365x2048.jpg 1365w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/07\/Herr-Orth_-18_retuschiert_-Michael-Orth-scaled.jpg 1706w\" sizes=\"(max-width: 200px) 100vw, 200px\" \/><br \/>\n<a href=\"https:\/\/www.medizin.uni-tuebingen.de\/de\/das-klinikum\/mitarbeiter\/profil\/5443\">Michael Orth<\/a><br \/>\nLaborleiter Molekulare Radioonkologie<br \/>\nKlinik f\u00fcr Radioonkologie, UKT T\u00fcbingen<\/p>\n<p><img loading=\"lazy\" class=\"alignleft wp-image-3660\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/Wael_Mansour.png\" alt=\"\" width=\"160\" height=\"213\" \/><br \/>\n<a href=\"https:\/\/www.uke.de\/allgemein\/arztprofile-und-wissenschaftlerprofile\/wissenschaftlerprofilseite_wael_mansour.html\">Wael Mansour<\/a><br \/>\nZentrum f\u00fcr Onkologie<br \/>\nKlinik f\u00fcr Strahlentherapie und Radioonkologie, UKE Hamburg<\/p>\n<\/div>\n<\/div><\/div><\/div><div class=\"panel-grid-cell\" id=\"pgc-3617-0-1\" ><div class=\"so-panel widget widget_sow-editor panel-first-child\" id=\"panel-3617-0-1-0\" data-index=\"1\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h2><b>Hintergrund und Ziele der Fokusgruppe<br \/>\n<\/b><\/h2>\n<p>Radiotherapie, die therapeutische Verwendung von Strahlung, stellt eine der wichtigsten Optionen f\u00fcr die heutige Behandlung von Tumorerkrankungen dar. Urspr\u00fcnglich auf der Annahme beruhend, dass entartete Gewebe und damit Tumore eine h\u00f6here Sensitivit\u00e4t gegen\u00fcber strahlungsvermittelter DNA-Sch\u00e4digung aufweisen als nicht entartete Gewebe (Normalgewebe), ist heute hingegen bekannt, dass viele Tumore eine gegen\u00fcber Normalgeweben signifikant h\u00f6here Resistenz gegen\u00fcber Strahlung aufweisen.<\/p>\n<p><img loading=\"lazy\" class=\"aligncenter wp-image-3473\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/03\/FG-IRS-Figure-215x300.png\" alt=\"\" width=\"573\" height=\"800\" srcset=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/03\/FG-IRS-Figure-215x300.png 215w, https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/03\/FG-IRS-Figure.png 950w\" sizes=\"(max-width: 573px) 100vw, 573px\" \/><\/p>\n<p>Um diesen Nachteil auszugleichen und um <strong>die Effektivit\u00e4t der Radiotherapie zu erh\u00f6hen<\/strong>, wird diese routinem\u00e4\u00dfig mit systemischen Therapien (Chemotherapien) kombiniert. Leider ist jedoch diese <strong>Kombination<\/strong> oftmals mit starken Nebenwirkungen assoziiert, was die Entwicklung von zielgerichtete-ren Behandlungsans\u00e4tzen (sogenannte \u201aTargeted therapies\u2018) erforderlich macht. Zu deren Entwicklung m\u00fcssen zun\u00e4chst determinante Faktoren (Gene\/RNAs\/Proteine), sogenannte Biomarker, f\u00fcr die Resistenz von Tumoren gegen\u00fcber Strahlung identifiziert und anschlie\u00dfend nach M\u00f6glichkeiten erschlossen werden, um mit der Funktion entsprechender Faktoren bestm\u00f6glich interferieren und dadurch die Effizienz der Radiotherapie maximal optimieren zu k\u00f6nnen.\u00a0Zu den hierf\u00fcr aktuell zur Verf\u00fcgung stehen-den M\u00f6glichkeiten z\u00e4hlen <strong>1. der Einsatz zielgerichteter Wirkstoffe<\/strong> (sogenannter \u201aTargeted drugs\u2018), bei denen es sich gleicherma\u00dfen um niedermolekulare Inhibitoren als auch um Makromolek\u00fcle wie Antik\u00f6rper (wie zum Beispiel Cetuximab\/Erbitux\u00ae), RNA-Molek\u00fcle oder Aptamere handeln kann, <strong>2. die Ver\u00e4nderung gewohnter Fraktionierungsschemata<\/strong>, wobei zumeist h\u00f6here Strahlungsdosen pro Fraktionseinheit verabreicht werden (Hypofraktionierung), <strong>3. die Verwendung von Strahlungsarten jenseits der althergebrachten R\u00f6ntgenstrahlung<\/strong> (wie zum Beispiel Protonen- und 12C-Ionenstrahlung) sowie 4. die Kombination der Radiotherapie mit immuntherapeutischen Behandlungsans\u00e4tzen wie beispielsweise Blockade der Programmed Death 1 (PD-1) \/ Programmed Death-Ligand 1 (PD-L1) Signalgebung mittels spezifischer Antik\u00f6rper. Die Fokusgruppe \u201eIntrinsische Strahlensensibilit\u00e4t\u201c der Arbeitsgemeinschaft \u201aExperimentelle Radioonkologie\u2018 widmet sich der Information und dem wissenschaftlichen Austausch \u00fcber dieses hoch relevante Themengebiet innerhalb der pr\u00e4klinischen strahlenbiologischen Forschung zwischen den einzelnen Disziplinen der Radioonkologie (Medizin\/Physik\/Biologie) in Deutschland und dar\u00fcber hinaus.<\/p>\n<p>\u00a0<\/p>\n<\/div>\n<\/div><\/div><div class=\"so-panel widget widget_icon-box\" id=\"panel-3617-0-1-1\" data-index=\"2\"><div class=\"thim-widget-icon-box thim-widget-icon-box-base\"><div class=\"wrapper-box-icon text-right  \" ><div class=\"smicon-box iconbox-left\"><div class=\"boxes-icon\" style=\"width: 100px;height: 100px;\"><span class=\"inner-icon\"><span class=\"icon\"><i class=\"fa fa-child\" style=\"color:#1e73be; font-size:30px; line-height:30px; vertical-align: middle;\"><\/i><\/span><\/span><\/div><div class=\"content-inner\"  style=\"width: calc( 100% - 100px - 15px);\"><div class=\"sc-heading article_heading\"><h3 class = \"heading__primary\" style=\"color: #1e73be;\">Derzeit Aktive Mitglieder<\/h3><\/div><div class=\"desc-icon-box\"><p >F\u00fcr weitere Informationen klicken Sie bitte auf die Namen.<\/p><\/div><\/div><\/div><!--end smicon-box--><\/div><\/div><\/div><div class=\"so-panel widget widget_lsow-accordion panel-last-child\" id=\"panel-3617-0-1-2\" data-index=\"3\"><div style=\"background-color:#b7d4e2;\" class=\"panel-widget-style\" ><div class=\"so-widget-lsow-accordion so-widget-lsow-accordion-default-d75171398898\">\n\n<div class=\"lsow-accordion style3\" data-toggle=\"true\">\n\n    \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Ali Sak<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Klinik f\u00fcr Strahlentherapie, Uniklinik Essen<\/span><\/p><p><span data-sheets-root=\"1\">Molekulare Radioonkologie Essen<\/span><\/p><p><span data-sheets-root=\"1\">ali.sak@uni-due.de<\/span><\/p><p><span data-sheets-root=\"1\">+491722153163<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Anna-Jasmina Donaubauer<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Translationale Strahlenbiologie<br \/>Strahlenklinik<\/span><\/p><p><span data-sheets-root=\"1\">Uniklinikum Erlangen<\/span><\/p><p>https:\/\/www.strahlenklinik.uk-erlangen.de\/forschung\/translatradbio\/clin-rad-immunbio\/<\/p><p><span data-sheets-root=\"1\">anna-jasmina.donaubauer@uk-erlangen.de<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Benjamin Frey<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Translationale Strahlenbiologie, Strahlenklinik<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum Erlangen, Friedrich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg<\/span><\/p><p>https:\/\/www.strahlenklinik.uk-erlangen.de\/forschung\/translatradbio\/<\/p><p><span data-sheets-root=\"1\">benjamin.frey@uk-erlangen.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 9131 85 44248<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Dennis Sohn<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Labor f\u00fcr Molekulare Radioonkologie<br \/>Klinik f\u00fcr Strahlentherapie und Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum D\u00fcsseldorf<\/span><\/p><p>https:\/\/www.uniklinik-duesseldorf.de\/patienten-besucher\/klinikeninstitutezentren\/klinik-fuer-strahlentherapie-und-radioonkologie\/forschungsschwerpunkte\/grundlagenforschung<\/p><p><span data-sheets-root=\"1\">Dennis.Sohn@hhu.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 211 81 06812<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Elena Sperk<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Mannheim Cancer Center, Medizinische Fakult\u00e4t Mannheim, Universit\u00e4t Heidelberg<\/span><\/p><p>https:\/\/www.linkedin.com\/in\/elena-sperk-0965a0180\/<\/p><p>\u00a0<\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Fabian Troschel<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Klinik f\u00fcr Strahlentherapie - Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum M\u00fcnster<\/span><\/p><p>https:\/\/web.ukm.de\/strahlentherapie-strahlenbio<\/p><p><span data-sheets-root=\"1\">fabian.troschel@ukmuenster.de<\/span><\/p><p><span data-sheets-root=\"1\">+492518355389<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Franz R\u00f6del<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Klinik f\u00fcr Strahlentherapie und Onkologie<br \/>Goethe Universit\u00e4t Frankfurt am Main<\/span><\/p><p><span data-sheets-root=\"1\">Molekulare Strahlenbiologie Frankfurt am Main<\/span><\/p><p>https:\/\/www.unimedizin-ffm.de\/einrichtungen\/kliniken\/zentrum-der-radiologie\/strahlentherapie\/unsere-klinik\/mitarbeiter\/strahlenbiologie<\/p><p><span data-sheets-root=\"1\">f.roedel@med.uni-frankfurt.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 176 29912332<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Ina Patties<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Experimentelle Strahlentherapie<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4t Leipzig, Klinik und Poliklinik f\u00fcr Strahlentherapie<\/span><\/p><p><span data-sheets-root=\"1\"><a class=\"in-cell-link\" href=\"http:\/\/www.linkedin.com\/in\/ina-patties\" target=\"_blank\" rel=\"noopener\">www.linkedin.com\/in\/ina-patties<\/a><\/span><\/p><p><span data-sheets-root=\"1\">ina.patties@medizin.uni-leipzig.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 341 9718492<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Johann Matschke<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Institut f\u00fcr Zellbiologie (Tumorforschung)<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum Essen<\/span><\/p><p>https:\/\/www.uni-due.de\/zmb\/members\/johann-matschke.php<\/p><p><span data-sheets-root=\"1\">johann.matschke@uk-essen.de<\/span><\/p><p><span data-sheets-root=\"1\">+492017234234<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Michael Orth<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum T\u00fcbingen (UKT), Klinik f\u00fcr Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Molekulare Radioonkologie T\u00fcbingen<\/span><\/p><p>https:\/\/www.medizin.uni-tuebingen.de\/de\/das-klinikum\/mitarbeiter\/profil\/5443<\/p><p><span data-sheets-root=\"1\">michael.orth@med.uni-tuebingen.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 160 91819048<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Nina Struve<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">AG Struve, Strahlenbiologie von p\u00e4diatrischen Hirntumoren, Labor f\u00fcr Strahlenbiologie &amp; Experimentelle Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum Hamburg-Eppendorf<\/span><\/p><p>https:\/\/www.uke.de\/kliniken-institute\/kliniken\/strahlentherapie-radioonkologie\/forschung\/strahlenbiologie-experimentelle-radioonkologie\/ag5-strahlenbiologie-von-kindlichen-hirntumoren\/index.html<\/p><p><span data-sheets-root=\"1\">ni.struve@uke.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 40741052358<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Sibylla Kohl<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">AG Molekulare Strahlenbiologie<br \/>Klink f\u00fcr Strahlentherapie und Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Philipps-Universit\u00e4t Marburg<\/span><\/p><p><span data-sheets-root=\"1\">sibylla.kohl@uni-marburg.de<\/span><\/p><p><span data-sheets-root=\"1\">+49 6421 28 21978<\/span><\/p><p><a href=\"https:\/\/www.ukgm.de\/ugm_2\/deu\/umr_rth\/umr_rth_team.php?id=13098\">https:\/\/www.ukgm.de\/ugm_2\/deu\/umr_rth\/umr_rth_team.php?id=13098<\/a><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Tina Jost<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">AG Molekular Radioonkologie, Translationale Strahlenbiologie, Strahlenklinik Erlangen<\/span><\/p><p><span data-sheets-root=\"1\">Uniklinikum Erlangen<\/span><\/p><p><a href=\"https:\/\/www.strahlenklinik.uk-erlangen.de\/forschung\/translatradbio\/mol-rad-onco\/\">Molekulare Radioonkologie - Strahlenklinik | Uniklinikum Erlangen<\/a><\/p><p><a href=\"https:\/\/www.strahlenklinik.uk-erlangen.de\/kontakt\/visitenkarte\/tina-jost-6818\/\"><span data-sheets-root=\"1\">Kontakt<\/span><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Udo Gaipl<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Translationale Strahlenbiologie an der Strahlenklinik Erlangen<\/span><\/p><p><span data-sheets-root=\"1\">Universit\u00e4tsklinikum Erlangen<\/span><\/p><p>https:\/\/www.strahlenklinik.uk-erlangen.de\/forschung\/translatradbio\/<\/p><p><span data-sheets-root=\"1\">udo.gaipl@uk-erlangen.de<\/span><\/p><p><span data-sheets-root=\"1\">+491708310606<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Ulrike Thei\u00df<\/div>\n\n            <div class=\"lsow-panel-content\"><p><span data-sheets-root=\"1\">Molekulare Strahlenbiologie<br \/>Klinik f\u00fcr Strahlentherapie und Radioonkologie<\/span><\/p><p><span data-sheets-root=\"1\">Philipps-Universit\u00e4t Marburg<\/span><\/p><p><a href=\"https:\/\/www.ukgm.de\/ugm_2\/deu\/umr_rth\/10904.html\">https:\/\/www.ukgm.de\/ugm_2\/deu\/umr_rth\/10904.html<\/a><\/p><p><span data-sheets-root=\"1\">ulrike.theiss@uni-marburg.de<\/span><\/p><p><span data-sheets-root=\"1\">+49-(0)6421-28-66058<\/span><\/p><\/div>\n\n        <\/div>\n\n        \n<\/div><\/div><\/div><\/div><\/div><div class=\"panel-grid-cell\" id=\"pgc-3617-0-2\" ><div class=\"so-panel widget widget_sow-editor panel-first-child\" id=\"panel-3617-0-2-0\" data-index=\"4\"><div class=\"so-widget-sow-editor so-widget-sow-editor-base\">\n<div class=\"siteorigin-widget-tinymce textwidget\">\n\t<h3>Highlights Fokusgruppe<\/h3>\n<\/div>\n<\/div><\/div><div class=\"so-panel widget widget_lsow-accordion\" id=\"panel-3617-0-2-1\" data-index=\"5\"><div class=\"so-widget-lsow-accordion so-widget-lsow-accordion-default-d75171398898\">\n<h3 class=\"widget-title\">Publikationen 2026<\/h3>\n<div class=\"lsow-accordion style3\" data-toggle=\"true\">\n\n    \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Weishaar D. et al., Phys Med Biol. 2026 Jan<\/div>\n\n            <div class=\"lsow-panel-content\"><p class=\"heading-title\">Impact of dose rate and its definition on the production of hydrogen peroxide in pure water<\/p>\n<p class=\"heading-title\">\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41397377\/\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Mladenov E. et al., Cells  2026 Jan<\/div>\n\n            <div class=\"lsow-panel-content\"><p class=\"heading-title\">Evidence for Quasi-High-LET Biological Effects in Clinical Proton Beams That Suppress c-NHEJ and Enhance HR and Alt-EJ<\/p><p>\u00a0<\/p><p><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41511369\/\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Kohl S. et al., Radiat Oncol. 2026 Feb<\/div>\n\n            <div class=\"lsow-panel-content\"><p class=\"heading-title\">CXCR2 affects sensitization of radioresistant HPV-negative head and neck squamous cell carcinoma cells by ABT-263<\/p>\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41680869\/\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Hessenow R. et al., Int J Radiat Oncol Biol Phys. 2026 Feb<\/div>\n\n            <div class=\"lsow-panel-content\">Homologous Recombination and Alternative End-Joining Repair Pathways are Important Determinants of Radiosensitivity to Proton Radiation Therapy\n\n<a href=\"https:\/\/www.redjournal.org\/article\/S0360-3016(26)00427-X\/fulltext\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Gorainow N. et al., Cell Death Dis. 2026 March <\/div>\n\n            <div class=\"lsow-panel-content\"><p class=\"c-article-title\" data-test=\"article-title\">Berzosertib enhances the sensitivity of pediatric diffuse midline glioma H3K27-altered cells to radiotherapy<\/p>\n<a href=\"https:\/\/www.nature.com\/articles\/s41419-026-08567-7\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">Brix N. et al., Mol Oncol. 2026 May<\/div>\n\n            <div class=\"lsow-panel-content\"><p class=\"heading-title\">LDAcoop: Integrating non-linear population dynamics into the analysis of clonogenic growth in vitro<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/41454442\/\"><img class=\"aligncenter size-medium wp-image-3684\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2025\/04\/PubMEd-300x200.png\" alt=\"\" width=\"300\" height=\"200\" \/><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n<\/div><\/div><\/div><div class=\"so-panel widget widget_lsow-accordion panel-last-child\" id=\"panel-3617-0-2-2\" data-index=\"6\"><div class=\"so-widget-lsow-accordion so-widget-lsow-accordion-default-d75171398898\">\n<h3 class=\"widget-title\">Projekte 2026<\/h3>\n<div class=\"lsow-accordion style3\" data-toggle=\"true\">\n\n    \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">BMFTR - SeniRad<\/div>\n\n            <div class=\"lsow-panel-content\"><p><strong>Strahlungsinduzierte Seneszenz: Implikationen f\u00fcr Normalgewebstoxizit\u00e4t und Tumortherapie-Versagen<\/strong><\/p><p>LMU M\u00fcnchen<\/p><p>Helmholtz Zentrum M\u00fcnchen<\/p><p>Universit\u00e4tsklinikum Essen<\/p><p>Johann Wolfgang Goethe-Universit\u00e4t Frankfurt am Main<\/p><p><a href=\"https:\/\/www.kvsf.de\/laufende-projekte\"><img class=\"aligncenter  wp-image-3903\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2026\/09\/Icon-WWW-300x290.jpg\" alt=\"\" width=\"143\" height=\"138\" \/><\/a><\/p><p class=\"heading-title\">\u00a0<\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">BMFTR - MetaC(h)roSS<\/div>\n\n            <div class=\"lsow-panel-content\"><p><strong>\u201eMetabolismus, Chromatin und Seneszenz nach Strahlentherapie\u201c<\/strong><\/p><p>Saarland University\u00a0<\/p><p>University of Duisburg-Essen\u00a0<\/p><p>Heidelberg University<a href=\"https:\/\/www.uni-due.de\/2026-08-12-verbundprojekt-metachross-will-gesundes-gewebe-bei-strahlentherapie-schuetzen\"><img class=\"aligncenter  wp-image-3903\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2026\/09\/Icon-WWW-300x290.jpg\" alt=\"\" width=\"143\" height=\"138\" \/><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">LOEWE - ADMIT <\/div>\n\n            <div class=\"lsow-panel-content\"><p><strong>Advanced Medical Physics in Imaging and Therapy<\/strong><\/p><p>Universit\u00e4t Marburg<\/p><p><a href=\"https:\/\/proloewe.de\/de\/loewe-vorhaben\/nach-themen\/admit\/\"><img class=\"aligncenter  wp-image-3903\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2026\/09\/Icon-WWW-300x290.jpg\" alt=\"\" width=\"143\" height=\"138\" \/><\/a><\/p><p class=\"heading-title\">\u00a0<\/p><\/div>\n\n        <\/div>\n\n        \n        <div class=\"lsow-panel\">\n\n            <div class=\"lsow-panel-title\">DFG - gROS <\/div>\n\n            <div class=\"lsow-panel-content\"><p><strong>Monte-Carlo-GPU-Modellierung von reaktiven Sauerstoffspezies (ROS) w\u00e4hrend der FLASH-Strahlentherapie<\/strong><\/p><p>Universit\u00e4t Marburg<\/p><p class=\"heading-title\"><a href=\"https:\/\/gepris.dfg.de\/project\/550953943\"><img class=\"aligncenter  wp-image-3903\" src=\"https:\/\/www.degro.org\/radiobiologie\/wp-content\/uploads\/sites\/11\/2026\/09\/Icon-WWW-300x290.jpg\" alt=\"\" width=\"143\" height=\"138\" \/><\/a><\/p><\/div>\n\n        <\/div>\n\n        \n<\/div><\/div><\/div><\/div><\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>#pgc-3617-0-0 , #pgc-3617-0-2 { width:20.038% } #pgc-3617-0-1 { width:59.925% } #pg-3617-0 .panel-grid-cell { float:left } #pl-3617 .panel-grid-cell .so-panel { margin-bottom:30px } #pl-3617 .panel-grid-cell .so-panel:last-child { margin-bottom:0px } #pg-3617-0 { margin-left:-15px;margin-right:-15px } #pg-3617-0 .panel-grid-cell { padding-left:15px;padding-right:15px } @media (max-width:780px){ #pg-3617-0 .panel-grid-cell <\/p>\n","protected":false},"author":43,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/pages\/3617"}],"collection":[{"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/users\/43"}],"replies":[{"embeddable":true,"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/comments?post=3617"}],"version-history":[{"count":17,"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/pages\/3617\/revisions"}],"predecessor-version":[{"id":3807,"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/pages\/3617\/revisions\/3807"}],"wp:attachment":[{"href":"https:\/\/www.degro.org\/radiobiologie\/wp-json\/wp\/v2\/media?parent=3617"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}