{"id":1015,"date":"2025-02-11T14:39:59","date_gmt":"2025-02-11T13:39:59","guid":{"rendered":"https:\/\/www.degro.org\/ag-stereotaxie\/?page_id=1015"},"modified":"2025-02-12T14:02:11","modified_gmt":"2025-02-12T13:02:11","slug":"sbrt-for-bone-metastases","status":"publish","type":"page","link":"https:\/\/www.degro.org\/ag-stereotaxie\/sbrt-for-bone-metastases\/","title":{"rendered":"SBRT for bone metastases"},"content":{"rendered":"<h1>Stereotactic radiotherapy for spine and non-spine bone metastases: A pattern-of-care analysis in German speaking countries<\/h1>\n<hr \/>\n<h4><span style=\"color: #000000;\">Study PI:<\/span><\/h4>\n<p>Dr. med. Franziska N\u00e4gler<br \/>\n<a href=\"Franziska.naegler@medizin.uni-leipzig.de\">Franziska.naegler@medizin.uni-leipzig.de<\/a><\/p>\n<p>Prof. Dr. Dr. Nils Nicolay<br \/>\n<a href=\"nils.nicolay@medizin.uni-leipzig.de\">nils.nicolay@medizin.uni-leipzig.de<\/a><\/p>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Study design:<\/span><\/h4>\n<ul>\n<li>online survey among radiation oncologists (ROs) registered with the interdisciplinary working group Radiosurgery and Stereotactic Radiotherapy of the German Society of Radiation Oncology (DEGRO) and German Society for Medical Physics (DGMP)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Study objectiev:<\/span><\/h4>\n<ul>\n<li>Bone metastases constitute a common indication for both conventional radiotherapy (RT) and stereotactic body radiotherapy (SBRT). Although in recent years guidelines have been proposed for SBRT of spine and non-spine metastases, little is known about the usage of bone SBRT and the actual patterns-of-care in German-speaking countries<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Project status:<\/span><\/h4>\n<ul>\n<li>Data collection completed<\/li>\n<li>manuscript currently under review<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Major findings and results:<\/span><\/h4>\n<ul>\n<li>35 % (75\/211) of registered ROs completed the online survey.<\/li>\n<li>ROs working in high-volume centers irradiating more than 100 patients with bone metastases annually represented the largest group with 58.7 %.<\/li>\n<li>Ablative SBRT was mostly performed for bone oligometastases (78.7 %).<\/li>\n<li>For symptom-directed palliative radiotherapy of bone metastases, the majority of responding physicians (84.3\u00a0%) still mostly recommended moderately hypofractionated treatment. Nevertheless, 60.9\u00a0% of participating ROs stated to use bone SBRT at least occasionally also for palliative purposes such as pain control.<\/li>\n<li>Survey also revealed a certain reluctance for the concomitant use of systemic therapies with bone SBRT and a heterogeneity regarding target volume definition and dosing for bone SBRT.<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h1>Stereotactic radiotherapy for bone metastases: a multicentre analysis<\/h1>\n<hr \/>\n<h4><span style=\"color: #000000;\">Study PI:<\/span><\/h4>\n<p>Dr. med. Franziska N\u00e4gler<br \/>\n<a href=\"Franziska.naegler@medizin.uni-leipzig.de\">Franziska.naegler@medizin.uni-leipzig.de<\/a><\/p>\n<p>Prof. Dr. Dr. Nils Nicolay<br \/>\n<a href=\"nils.nicolay@medizin.uni-leipzig.de\">nils.nicolay@medizin.uni-leipzig.de<\/a><\/p>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Collaboration partners:<\/span><\/h4>\n<ul>\n<li>Dr. med. Lena K\u00e4stner\/ PD Dr. med. Dr. rer. nat. Judit Boda-Heggemann, University Hospital MannheimDr. med. Olaf Wittenstein\/ PD Dr. Oliver Blanck, University Hospital Schleswig-Holstein<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Study design:<\/span><\/h4>\n<ul>\n<li>multicenter retrospective study<\/li>\n<li>The retrospective analysis will help to design a prospective registry for bone SBRT that will be open for participation for all WG members<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Study objective:<\/span><\/h4>\n<ul>\n<li>To evaluate efficacy and safety of SBRT for bone metastases in a defined patient population (several subgroups) and multicenter setting<\/li>\n<li>To identify patients who will benefit most from this approach and to establish binding SBRT-dose concepts and better define the combination with systemic treatments<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Project status:<\/span><\/h4>\n<ul>\n<li>Data collection for retrospective analysis<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h4><span style=\"color: #000000;\">Major findings and results:<\/span><\/h4>\n","protected":false},"excerpt":{"rendered":"<p>Stereotactic radiotherapy for spine and non-spine bone metastases: A pattern-of-care analysis in German speaking countries<\/p>\n<p>Study PI:<br \/>\nDr. med. Franziska N\u00e4gler<br \/>\nFranziska.naegler@medizin.uni-leipzig.de<br \/>\nProf. Dr. Dr. Nils Nicolay<br \/>\nnils.nicolay@medizin.uni-leipzig.de<br \/>\n&nbsp;<br \/>\nStudy design:<\/p>\n<p>online survey among radiation oncologists (ROs) registered <\/p>\n","protected":false},"author":8,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/pages\/1015"}],"collection":[{"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/users\/8"}],"replies":[{"embeddable":true,"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/comments?post=1015"}],"version-history":[{"count":5,"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/pages\/1015\/revisions"}],"predecessor-version":[{"id":1025,"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/pages\/1015\/revisions\/1025"}],"wp:attachment":[{"href":"https:\/\/www.degro.org\/ag-stereotaxie\/wp-json\/wp\/v2\/media?parent=1015"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}